Industrial property,Patents

The concept of “active ingredient”: Insights from the Halozyme referral (C-456/24)

By Natali Goginashvili at Associate, HOYNG ROKH MONEGIER, Paris Background The applicant, Halozyme Inc, specializes in drug delivery technologies for emerging and established therapies. Its core technology ENHANZE® is based on recombinant human hyaluronidase ("rHuPH20"), which is a drug delivery enzyme that locally breaks down human hyaluronic acid, and when co-formulated with other drugs, facilitates their subcutaneous delivery after injection. Halozyme has partnered for ENHANZE® with multiple pharmaceutical companies, including Roche who markets a combination of trastuzumab and rHuPH20 branded as Herceptin®. Trastuzumab is a known active ingredient, which is a monoclonal antibody widely used in the treatment of breast...